Heparin has been used extensively as an antithrombotic and anticoagulant for close to 100
years. This anticoagulant activity is attributed mainly to the pentasaccharide sequence, …

The formation of acquired drug resistance is a major reason for the failure of anti-cancer
therapies after initial response. Here, we introduce a novel model of acquired oxaliplatin …

Whilst an established discipline in many markets, to both the uninitiated and experienced alike,
Transition Management can appear a complex and confusing subject area. This is in part …

… Removal of the N-sulfate from heparin produced a material which had no measurable
activity in any assay. Heparin which had been de-N-sulfated and then re-N-acetylated (N-acetyl) …

… Five independent experiments were run for Clexane LMWH (n = 5) and Innohep LMWH (n
= 5); only four independent experiments were run for Fragmin LMWH (n = 4), so these data …

… Most of the participants in this study were 489 Caucasian (n=23) with only one participant
from a Hispanic background. While resting and 490 postprandial FMD has previously been …

… Using a metabolic labelling approach to incorporate N-azido-galactosamine into mucin-type
O-link glycans, proteins harbouring such modification were enriched and the total number of …

This article seeks to establish whether an issue-attention cycle of the type described by
Downs for policy relating to the environment is typical of all policy areas in the United States. …

… Error bars represent 95% confidence limits (n = 2 for one stage clotting and FIXa assays;
n = 1 for FIX chromogenic assays). … Error bars represent 95% confidence limits (n = 6). …

Recombinant protein products such as monoclonal antibodies (mAbs) for use in the clinic
must be clear of host cell impurities such as host cell protein (HCP), DNA/RNA, and high …