User profiles for Michael A. Silverman

Michael Silverman

Assistant Professor of Pediatrics
Verified email at chop.edu
Cited by 2048

[HTML][HTML] Dapagliflozin and cardiovascular outcomes in type 2 diabetes

…, ET Kato, A Cahn, MG Silverman… - … England Journal of …, 2019 - Mass Medical Soc
Background The cardiovascular safety profile of dapagliflozin, a selective inhibitor of sodium–glucose
cotransporter 2 that promotes glucosuria in patients with type 2 diabetes, is …

Association between lowering LDL-C and cardiovascular risk reduction among different therapeutic interventions: a systematic review and meta-analysis

MG Silverman, BA Ference, K Im, SD Wiviott… - Jama, 2016 - jamanetwork.com
Importance The comparative clinical benefit of nonstatin therapies that reduce low-density
lipoprotein cholesterol (LDL-C) remains uncertain. Objective To evaluate the association …

Multiple-center, randomized, placebo-controlled, double-blind study of the nitric oxide synthase inhibitor 546C88: effect on survival in patients with septic shock

…, L Holzapfel, D Breen, MS Silverman… - Critical care …, 2004 - journals.lww.com
Michael S. Silverman, Oshawa General Hospital, Oshawa, Ontario, Canada; Professor
Jukka Takala, Intensive Care Unit, Kuopio University Hospital, Kuopio, Finland; Dr. John …

Intercellular signalling in Vibrio harveyi: sequence and function of genes regulating expression of luminescence

…, M Wright, RE Showalter, MR Silverman - Molecular …, 1993 - Wiley Online Library
Density‐dependent expression of luminescence in Vibrio harveyi is regulated by the
concentration of an extracellular signal molecule (autoinducer) in the culture medium. A …

Multiple signalling systems controlling expression of luminescence in Vibrio harveyi: sequence and function of genes encoding a second sensory pathway

BL Bassler, M Wright, MR Silverman - Molecular microbiology, 1994 - Wiley Online Library
Density‐dependent expression of luminescence in Vibrio harveyl is regulated by the
concentration of extracellular signal molecules (autoinducers) in the culture medium. One signal‐…

[HTML][HTML] An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer's disease–associated Aβ oligomers

…, JC Houzel, H Decker, MA Silverman… - The Journal of …, 2012 - Am Soc Clin Investig
Defective brain insulin signaling has been suggested to contribute to the cognitive deficits in
patients with Alzheimer’s disease (AD). Although a connection between AD and diabetes …

Fecal microbiota transplantation plus anti-PD-1 immunotherapy in advanced melanoma: a phase I trial

…, N Segata, SMM Haeryfar, BH Mullish, MS Silverman… - Nature medicine, 2023 - nature.com
Fecal microbiota transplantation (FMT) represents a potential strategy to overcome resistance
to immune checkpoint inhibitors in patients with refractory melanoma; however, the role of …

Effect of dapagliflozin on heart failure and mortality in type 2 diabetes mellitus

ET Kato, MG Silverman, O Mosenzon, TA Zelniker… - Circulation, 2019 - Am Heart Assoc
Background: In DECLARE-TIMI 58 (Dapagliflozin Effect on Cardiovascular Events–Thrombolysis
in Myocardial Infarction 58), the sodium-glucose cotransporter 2 inhibitor dapagliflozin …

[HTML][HTML] Safety and efficacy of TG101348, a selective JAK2 inhibitor, in myelofibrosis

…, M Talpaz, RM Stone, MH Silverman… - Journal of Clinical …, 2011 - ncbi.nlm.nih.gov
Silverman, TargeGen (C) Stock Ownership: Jolene Shorr, TargeGen Honoraria: Catriona
Jamieson, TargeGen Research Funding: Animesh Pardanani, TargeGen, Cytopia; Jason R …

Cutaneous malignant melanoma

…, JM Cummins, H Pantle, MA Silverman… - Mayo clinic …, 2006 - Elsevier
Skin cancer has become the most common neoplasm in the United States. With early diagnosis
and appropriate management, most skin cancers have an overall 5-year survival rate of …