Derivatives of imidazole. I. Synthesis and reactions of imidazo [1, 2-α] pyridines with analgesic, antiinflammatory, antipyretic, and anticonvulsant activity

…, A Biancotti, A Gamba, W Murmann - Journal of medicinal …, 1965 - ACS Publications
… The bromination of p-methylsulfoxyacetophenone with bromine in benzene led to p-methylmercapto-w-dibromoacetophenone. …
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Derivatives of imidazole. III. Synthesis and pharmacological activities of nitriles, amides, and carboxylic acid derivatives of imidazo [1, 2-a] pyridine

…, E Zefelippo, N De Toma, W Murmann - Journal of Medicinal …, 1969 - ACS Publications
A number of improved laboratory procedures for the synthesis of imidazol 1, 2-«, Jpyridine
derivatives are re-ported. The resulting compounds, which are structurally related to indole …

Derivatives of imidazole. II. Synthesis and reactions of imidazo [1, 2-α] pyrimidines and other bi-and tricyclic imidazo derivatives with analgesic, antiinflammatory …

…, P Rugarli, A Gamba, A Olivi, W Murmann - Journal of Medicinal …, 1966 - ACS Publications
The synthesis and pharmacological properties of some derivatives of imidazo [l, 2-o] pyrimidine,
lH-imidazo-[l, 2-d] tetrazole, imidazo [2, l-6] thiazole, lH-imidazo [l, 2-b]-s-triazole, and …

Imidazole derivatives. IV. Synthesis and pharmacologic activity of oxygenated derivatives of imidazo [1, 2-a] pyridine

…, N De Toma, A Gamba, W Murmann… - Journal of Medicinal …, 1970 - ACS Publications
In the course of screening imidazo [l, 2-a] pyridines, new oxygenated derivatives were
synthesized: aldehydes, ketones, their derivatives, and the corresponding alcohols. Some …

Relationship between configuration and adrenergic β-receptor blocking activity of optical isomers of 1-(4-nitrophenyl)-2-isopropylaminoethanol (INPEA)

L Almirante, W Murmann - Journal of Medicinal Chemistry, 1966 - ACS Publications
Received February 10. loen l-(4-Nitrophenyl)-2-isopropylaminoet. hanol (I ATEA), a highly
specific adrenergic/3-receptor, inhibitor, has been resolved into its optically active isomers. …

[HTML][HTML] Genome Sequence Analysis of Clostridium chauvoei Strains of European Origin and Evaluation of Typing Options for Outbreak Investigations

…, C Werckenthin, C Baumbach, W Murmann… - Frontiers in …, 2021 - frontiersin.org
Black quarter caused by Clostridium (C.) chauvoei is an important bacterial disease that affects
cattle and sheep with high mortality. A comparative genomics analysis of 64 C. chauvoei …

Amino-methylchromones, brain stem stimulants and pentobarbital antagonists

I Setnikar, W Murmann, MJ Magistretti… - Journal of Pharmacology …, 1960 - ASPET
The CNS stimulant activity of two new brain stem stimulants, 2,3-dimethyl-7-methoxy-morpholinomethylchromone
hydrochloride (Rec 7- 0105) and 3-methyl-7-methoxy-8-dimethylamino…

Effects of cicloxilic acid on CCl4-induced liver injury.

G Bramanti, W Murmann, P Pierini… - Arzneimittel …, 1978 - europepmc.org
The effects of cis-2-hydroxy-2-phenyl-cyclohexanecarboxilic acid (cicloxilic acid) on the liver
injury produced by carbon tetrachloride poisoning were studied in rats. It was found that oral …

N-substituted 8-aminomethylchromones, a new class of central nervous system stimulants

I Setnikar, W Murmann, MJ Magistretti… - Journal of Medicinal …, 1960 - ACS Publications
The observation1 that high doses of JV-substituted 6-amino-methylchromones or fiavones
provoke convulsions due to excitation of the central nervous system (CNS) has led us to start …

N-substituted 7-methoxy-8-aminomethylchromones and flavones: new brain-stem stimulants

P Da Re, L Verlicchi, I Setnikar, W Murmann… - Nature, 1959 - nature.com
THE pharmacological screening of various chromone and flavone derivatives has led to the
discovery of a new class of brain-stem stimulants, the N-substituted aminomethyl derivatives …