Peripheral arterial disease (PAD) is a chronic, lifestyle-limiting disease and is an independent
predictor of cardiovascular and cerebrovascular ischemic events. Despite the recognition …

Coronary chronic total occlusions (CTOs) are commonly encountered complex lesions
identified in 15% of all patients referred for coronary angiography. Chronic total occlusion …

… 6.1 events per hour, p = 0.015). Mean HbA1c and systolic blood pressure were significantly
lowered in the liraglutide group (p < 0.0001). Similar to previous trials most of the adverse …

Background The cardiovascular effect of liraglutide, a glucagon-like peptide 1 analogue,
when added to standard care in patients with type 2 diabetes, remains unknown. Methods In …

Background Regulatory guidance specifies the need to establish cardiovascular safety of
new diabetes therapies in patients with type 2 diabetes in order to rule out excess …

Background Atherosclerotic plaques that lead to acute coronary syndromes often occur at
sites of angiographically mild coronary-artery stenosis. Lesion-related risk factors for such …

Background The cardiovascular effects of adding once-weekly treatment with exenatide to
usual care in patients with type 2 diabetes are unknown. Methods We randomly assigned …

OBJECTIVES The study compared procedural outcomes and long-term survival for patients
undergoing percutaneous coronary intervention (PCI) of a chronic total coronary artery …

Background In a randomized, controlled trial that compared liraglutide, a glucagon-like
peptide 1 analogue, with placebo in patients with type 2 diabetes and high cardiovascular risk …

Background Degludec is an ultralong-acting, once-daily basal insulin that is approved for
use in adults, adolescents, and children with diabetes. Previous open-label studies have …