To correlate the arrhythmogenic effects of maternal autoantibodies with the genesis of
congenital heart block, female BALB/c mice were immunized with human recombinant 48-kDa …

Troubled automotive suppliers are in some ways the most complex and difficult turnaround
companies imaginable. Their customers have almost unparalleled power, the industry is both …

Normal platelet function is critical to blood hemostasis and maintenance of a closed
circulatory system. Heightened platelet reactivity, however, is associated with cardiometabolic …

Access of intracellular Ags SSA/Ro and SSB/La to cognate maternal autoantibodies is
unexplained despite their strong association with congenital heart block. To investigate the …

Recent studies indicate both clinical and mechanistic links between atherosclerotic heart
disease and intestinal microbial metabolism of certain dietary nutrients producing …

L-carnitine, a nutrient in red meat, was recently reported to accelerate atherosclerosis via a
metaorganismal pathway involving gut microbial trimethylamine (TMA) formation and host …

Trimethylamine N-oxide (TMAO) is a gut microbiota–derived metabolite that enhances both
platelet responsiveness and in vivo thrombosis potential in animal models, and TMAO …

Lysyl oxidase is an extracellular enzyme that controls the maturation of collagen and elastin.
Lysyl oxidase and collagen III often show similar expression patterns in fibrotic tissues. …

BACKGROUND. l-Carnitine, an abundant nutrient in red meat, accelerates atherosclerosis in
mice via gut microbiota–dependent formation of trimethylamine (TMA) and trimethylamine N…

Here, we show that apolipoprotein A1 (apoA1), the major protein component of high density
lipoprotein (HDL), through both innate and adaptive immune processes, potently …