The goal of this article is to obtain an age/period/cohort (A/P/C) decomposition of historical
US mortality improvement. Two different routes to achieving this goal are considered. In the …

With longevity now a clearly recognized systematic trend risk, institutions and individuals are
looking for guidance in better understanding their exposure. They also seek assistance in …

Increases in longevity risk are real, large, and best transferred to the insurance/reinsurance
sector, where there is a natural offset. The magnitude, drivers, and sensitivity of longevity …

This article explores the current state of longevity modeling by borrowing from the investment
paradigm of fundamental vs. technical approaches, determining where there is common …

Cell migration is crucial for efficient immune responses and is aberrantly used by cancer cells
during metastatic dissemination. Amoeboid migrating cells use myosin II-powered blebs to …

This Special Issue of the North American Actuarial Journal (NAAJ) contains nine articles
that contribute to the advances in predictive analytics with a wide range of applications in …

Advances in modeling and algorithms, combined with growth in computing resources, have
enabled simulations of multiphysics–multiscale phenomena that can greatly enhance our …

Cell migration plays a pivotal role in various biological processes including cancer
dissemination and successful metastasis, where the role of mechanical signals is increasingly …

… Toronto Star, 20111 “Underestimated longevity is “the elephant in the room,” said George
Graziani, a senior vice-president at Swiss Re in Canada who is promoting so-called longevity …

Cell migration is crucial for cancer dissemination. We find that AMP-activated protein kinase
(AMPK) controls cell migration by acting as an adhesion sensing molecular hub. In 3-…