On-line medical control versus protocol-based prehospital care

SJ Rottman, DL Schriger, G Charlop, JH Salas… - Annals of emergency …, 1997 - Elsevier
Study objective: To compare on-scene time, appropriateness of therapy, and accuracy of
paramedic clinical assessments when prehospital care was provided with the use of on-line …

[HTML][HTML] Culture-independent discovery of the malacidins as calcium-dependent antibiotics with activity against multidrug-resistant Gram-positive pathogens

BM Hover, SH Kim, M Katz, Z Charlop-Powers… - Nature …, 2018 - nature.com
Despite the wide availability of antibiotics, infectious diseases remain a leading cause of
death worldwide 1. In the absence of new therapies, mortality rates due to untreatable …

Multiplexed metagenome mining using short DNA sequence tags facilitates targeted discovery of epoxyketone proteasome inhibitors

JG Owen, Z Charlop-Powers… - Proceedings of the …, 2015 - National Acad Sciences
In molecular evolutionary analyses, short DNA sequences are used to infer phylogenetic
relationships among species. Here we apply this principle to the study of bacterial biosynthesis, …

Global biogeographic sampling of bacterial secondary metabolism

Z Charlop-Powers, JG Owen, BVB Reddy, MA Ternei… - Elife, 2015 - elifesciences.org
10.7554/eLife.05048.001 Recent bacterial (meta)genome sequencing efforts suggest the
existence of an enormous untapped reservoir of natural-product-encoding biosynthetic gene …

Chemical-biogeographic survey of secondary metabolism in soil

Z Charlop-Powers, JG Owen… - Proceedings of the …, 2014 - National Acad Sciences
In this study, we compare biosynthetic gene richness and diversity of 96 soil microbiomes from
diverse environments found throughout the southwestern and northeastern regions of the …

The major glycoprotein allergen from Arachis hypogaea, Ara h 1, is a ligand of dendritic cell-specific ICAM-grabbing nonintegrin and acts as a Th2 adjuvant in vitro

…, ZY Kucuk, Z Charlop-Powers, G Grishina… - The Journal of …, 2006 - journals.aai.org
Nonmammalian glycan structures from helminths act as Th2 adjuvants. Some of these
structures are also common on plant glycoproteins. We hypothesized that glycan structures …

Blood flow and metabolism in locally advanced breast cancer: relationship to response to therapy

…, JR Gralow, GK Ellis, A Charlop… - Journal of Nuclear …, 2002 - Soc Nuclear Med
… 1 where A(t) is the time-varying tissue activity in kBq/g, C b (t) is the time-varying blood
activity in kBq/mL, F is blood flow in mL/min/g, V d is water distribution volume in mL/g, and λ is …

antiSMASH 6.0: improving cluster detection and comparison capabilities

…, AM Kloosterman, Z Charlop-Powers… - Nucleic acids …, 2021 - academic.oup.com
Many microorganisms produce natural products that form the basis of antimicrobials,
antivirals, and other drugs. Genome mining is routinely used to complement screening-based …

Increasing spontaneous verbal responding in autustic children using a time delay procedure

MH Charlop, L Schreibman… - Journal of applied …, 1985 - Wiley Online Library
One oft‐cited problem with teaching speech skills to autistic children isthe failure of the
speech to be spontaneous. That is, the children's speech often remains underthe control of the …

Using aberrant behaviors as reinforcers for autistic children

MH Charlop, PF Kurtz, FG Casey - Journal of applied behavior …, 1990 - Wiley Online Library
In a series of experiments, we assessed the efficacy of using autistic children's aberrant
behaviors as reinforcers to increase their correct task responding. In Experiment 1, reinforcer …