User profiles for B. Leonard
Brian M LeonardUniversity of Wyoming Verified email at uwyo.edu Cited by 3793 |
The olfactory bulbectomized rat as a model of depression: an update
JP Kelly, AS Wrynn, BE Leonard - Pharmacology & therapeutics, 1997 - Elsevier
The olfactory bulbectomized (OB) rat has been proposed as an animal model of depression.
The following behavioural changes have been observed following bilateral olfactory …
The following behavioural changes have been observed following bilateral olfactory …
Depression, stress and immunological activation: the role of cytokines in depressive disorders
TJ Connor, BE Leonard - Life sciences, 1998 - Elsevier
Traditionally, both stress and depression have been associated with impaired immune function
and increased susceptibility to infectious and neoplastic disease. However over the last …
and increased susceptibility to infectious and neoplastic disease. However over the last …
Mechanistic explanations how cell-mediated immune activation, inflammation and oxidative and nitrosative stress pathways and their sequels and concomitants play a …
B Leonard, M Maes - Neuroscience & Biobehavioral Reviews, 2012 - Elsevier
This paper reviews that cell-mediated-immune (CMI) activation and inflammation contribute
to depressive symptoms, including anhedonia; anxiety-like behaviors; fatigue and somatic …
to depressive symptoms, including anhedonia; anxiety-like behaviors; fatigue and somatic …
A stable and accurate convective modelling procedure based on quadratic upstream interpolation
BP Leonard - Computer methods in applied mechanics and …, 1979 - Elsevier
A convective modelling procedure is presented which avoids the stability problems of central
differencing while remaining free of the inaccuracies of numerical diffusion associated with …
differencing while remaining free of the inaccuracies of numerical diffusion associated with …
How should we define health?
…, H Van Der Horst, AR Jadad, D Kromhout, B Leonard… - Bmj, 2011 - bmj.com
The WHO definition of health as complete wellbeing is no longer fit for purpose given the
rise of chronic disease. Machteld Huber and colleagues propose changing the emphasis …
rise of chronic disease. Machteld Huber and colleagues propose changing the emphasis …
The ULTIMATE conservative difference scheme applied to unsteady one-dimensional advection
BP Leonard - Computer methods in applied mechanics and …, 1991 - Elsevier
… (b) Exact solution after translating 45 Ax to the right. … but the normalized ~b I will still depend
most strongly on 4)[. … ); in the Sweby diagram (see Appendix B) the function forms portion of a …
most strongly on 4)[. … ); in the Sweby diagram (see Appendix B) the function forms portion of a …
Simple high‐accuracy resolution program for convective modelling of discontinuities
BP Leonard - International journal for numerical methods in …, 1988 - Wiley Online Library
… Figure l(b) shows the same information in terms of the locally normalized variable … The
corresponding normalized interpolations are shown in Figure 2(b) for a specific value of &( <0-5). …
corresponding normalized interpolations are shown in Figure 2(b) for a specific value of &( <0-5). …
APOBEC3B is an enzymatic source of mutation in breast cancer
Several mutations are required for cancer development, and genome sequencing has revealed
that many cancers, including breast cancer, have somatic mutation spectra dominated …
that many cancers, including breast cancer, have somatic mutation spectra dominated …
Multiple phases of molybdenum carbide as electrocatalysts for the hydrogen evolution reaction
… p-Phenylenediamine (pPDA) was used as the precursor to produce η-MoC (Figure 1 b) at
1050 C with zero dwell time. FeCl 3 was mixed with the amine–metal oxide to help stabilize …
1050 C with zero dwell time. FeCl 3 was mixed with the amine–metal oxide to help stabilize …
Interactions between location and task affect the spatial and directional firing of hippocampal neurons
EJ Markus, YL Qin, B Leonard, WE Skaggs… - Journal of …, 1995 - Soc Neuroscience
… First half of the random task (a), second half of the random task (b), first half of the directed
task (c), second half of the directed task (d). A and B depict the data from the circular platform, …
task (c), second half of the directed task (d). A and B depict the data from the circular platform, …